Archetype Feature Distributions
| Tcells | Myeloid | Stromal | Treg | CD4 Tcells | CD8 Tcells | Monocytes | Macrophages | cDC2 | cDC1 |
|---|---|---|---|---|---|---|---|---|---|
| Low | Low | High | Low | Low | Very High | Low | Very High | Variable | Very Low |
Potential Origin of this Archetype
Late Wound healing, CD8, Macrophage Axis, Susstained by CX3CR1 signalling
Archetype Tumor transcriptomic program
Cell Dvision (G1-S ; G2-M), Fibrosis, EMT
Archetype Chemokines Expressed
CCL26, CCL27, CCL28, CCR10, CXC3CL1, CX3CR1
Archetype Immune Transcriptomic Programs
PD1-PDL1, High Exhaustion, IFN,TNFa signalling
Immune Archetype Gene Signature
Table of Archetype Feature Scores
Table of Archetype feature flow Populations
Table of Archetype non feature flow Populations
Histology Abbreviations
PSC = Papillary Serous Cystadenocarcinoma SCC = Squamous Cell Carcinoma NOS EA = Endometriod Adenocarcinoma S = Sarcoma NOS
| Sample | Gender | Race | Ethnicity | BMI | Age | T Stage | N Stage | M Stage | Grade | Histology | Tumor type | Extraction Site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IPIGYN059.T1 | Female | White | Non Hispanic or Latino | 42.67 | 54 | 1c | X | G2: Moderately differentiated (intermediate grade) | EA | Primary | ovary | |
| IPIGYN096.T1 | Female | Other | Hispanic or Latino | 42 | 70 | 3a | X | 1 | G3: Poorly differentiated (high grade) | PSC | Primary | uterus |
| IPIGYN099.T1 | Female | Other | Non Hispanic or Latino | 25 | 55 | 1b | 0 | G1: Well differentiated (low grade) | EA | Primary | ||
| IPIHNSC021.T1 | Female | White | Not reported | 20.27 | 42 | 4b | X | 0 | G3: Poorly differentiated (high grade) | SCC | Primary | paranasal sinus |
| IPIHNSC024.T1 | Female | White | Non Hispanic or Latino | 25.2 | 74 | 4a | X | G3: Poorly differentiated (high grade) | Other | Primary | nasal cavity | |
| IPIMELB003.T1 | Male | |||||||||||
| IPISRC015.T1 | Male | Black or African American | Non Hispanic or Latino | 46 | 40 | 2a | 1 | 1 | G3: Poorly differentiated (high grade) | S | Metastasis | inguinal part of abdomen |