Archetype Feature Distributions
Tcells | Myeloid | Stromal | Treg | CD4 Tcells | CD8 Tcells | Monocytes | Macrophages | cDC2 | cDC1 |
---|---|---|---|---|---|---|---|---|---|
Low | Low | Variable | Variable | Variable | Variable | Very High | Very Low | Low | Low |
Potential Origin of this Archetype
Early Wound healing, Tissue resident T cells, Supressive T reg, Neutrophils Axis, Sustained by IL1 signalling
Archetype Tumor transcriptomic program
Cell Dvision (G1-S ; G2-M), Proteasome pathway, Autophagy
Archetype Chemokines Expressed
N/A
Archetype Immune Transcriptomic Programs
Tissue Resident T cells (Trem), IL1b, ARG1 signalling, Suppresive Tregs, Neutrophils
Immune Archetype Gene Signature
Table of Archetype Feature Scores
Table of Archetype feature flow Populations
Table of Archetype non feature flow Populations
Histology Abbreviations
ADC = Adenocarcinoma NOS PSC = Papillary Serous Cystadenocarcinoma PC = Papillary Carcinoma C = Carcinoma NOS SCC = Squamous Cell Carcinoma NOS CCC = Clear Cell Carcinoma NOS EA = Endometriod Adenocarcinoma NET = Neuroendocrine Tumor TCC = Transitional Cell Carcinoma NOS, CHO = Cholangiocarcinoma
Sample | Gender | Race | Ethnicity | BMI | Age | T Stage | N Stage | M Stage | Grade | Histology | Tumor type | Extraction Site |
---|---|---|---|---|---|---|---|---|---|---|---|---|
IPIBLAD013.T1 | Male | White | Not reported | 26 | 60 | 4a | 0 | G3: Poorly differentiated (high grade) | C | Primary | ||
IPIBLAD024.T1 | Female | Asian | Non Hispanic or Latino | 28 | 77 | 3a | X | G3: Poorly differentiated (high grade) | C | Primary | Ureter | |
IPICRC035.T1 | Male | White | Non Hispanic or Latino | 31.31 | 39 | 3 | 1c | G1: Well differentiated (low grade) | ADC | Primary | rectum | |
IPICRC057.T1 | Male | Other | Hispanic or Latino | 31.28 | 64 | 4a | 2 | 0 | G1: Well differentiated (low grade) | ADC | Primary | |
IPICRC064.T1 | Female | White | Non Hispanic or Latino | 25.75 | 74 | 3 | 0 | 0 | G3: Poorly differentiated (high grade) | ADC | Primary | transverse colon |
IPICRC072.T1 | Female | White | Non Hispanic or Latino | 34.2 | 68 | 3 | 0 | G2: Moderately differentiated (intermediate grade) | ADC | Primary | caecum | |
IPICRC074.T1 | Female | Other | Hispanic or Latino | 31.7 | 34 | 3 | 0 | G2: Moderately differentiated (intermediate grade) | ADC | Primary | caecum | |
IPICRC077.T1 | Male | Asian | Non Hispanic or Latino | 31.94 | 69 | 2 | 1 | G2: Moderately differentiated (intermediate grade) | ADC | Primary | transverse colon | |
IPICRC080.T1 | Female | White | Non Hispanic or Latino | 32.77 | 89 | 3 | 0 | G2: Moderately differentiated (intermediate grade) | ADC | Primary | caecum | |
IPIGYN011.T1 | Female | Other | Hispanic or Latino | 30.3 | 36 | 3 | X | G3: Poorly differentiated (high grade) | EA | Primary | ovary | |
IPIGYN011.T2 | Female | Other | Hispanic or Latino | 30.3 | 36 | 3 | X | G3: Poorly differentiated (high grade) | EA | Primary | ovary | |
IPIGYN018.T2 | Female | White | Non Hispanic or Latino | 39.03 | 61 | 3c | 1 | G3: Poorly differentiated (high grade) | C | Primary | ovary | |
IPIGYN109.T1 | Female | White | Non Hispanic or Latino | 22.82 | 57 | 3c | 1 | X | G3: Poorly differentiated (high grade) | PSC | Primary | pelvic region element |
IPIHEP001.T1 | Female | White | Non Hispanic or Latino | 23 | 66 | 1 | 0 | G2: Moderately differentiated (intermediate grade) | CHO | Primary | gall bladder | |
IPIHEP017.T1 | Male | White | Non Hispanic or Latino | 25 | 70 | 4 | 0 | G3: Poorly differentiated (high grade) | ADC | Primary | ||
IPIHNSC061.T1 | Male | Asian | Non Hispanic or Latino | 19.35 | 67 | 4a | 2 | 0 | G2: Moderately differentiated (intermediate grade) | SCC | Primary | larynx |
IPIHNSC073.T1 | Female | White | Not reported | 24.95 | 69 | 4a | 3 | 0 | Not Available | SCC | LocalRecurrence | oral cavity |
IPIKID060.T1 | Male | Other | Hispanic or Latino | 20 | 78 | 1b | X | G3: Poorly differentiated (high grade) | CCC | Primary | right kidney | |
IPIKID106.T1 | Male | White | Non Hispanic or Latino | 21 | 65 | 3a | 0 | 1 | G2: Moderately differentiated (intermediate grade) | CCC | Primary | left kidney |
IPILUNG009.T1 | Male | White | Non Hispanic or Latino | 34 | 73 | 2a | 0 | G3: Poorly differentiated (high grade) | ADC | Primary | lower lobe of left lung | |
IPILUNG051.T1 | Female | White | Non Hispanic or Latino | 19 | 59 | 1a | 0 | G2: Moderately differentiated (intermediate grade) | ADC | Primary | lower lobe of left lung | |
IPIMEL056.T1 | Male | White | Non Hispanic or Latino | 28 | 41 | 4b | 3 | 1 | Not Available | Nevi & Melanomas | Metastasis | left axillary sentinel lymph node |
IPIMEL105.T2 | Male | White | Non Hispanic or Latino | 30 | 69 | X | 3 | Not Available | Nevi & Melanomas | Metastasis | Left axillary sentinel lymph node | |
IPIMEL208.T1 | Female | White | Non Hispanic or Latino | 14 | 59 | 1 | 0 | 0 | Not Available | Other | Primary | Spleen |
IPIMEL221.T1 | Female | White | Non Hispanic or Latino | 38 | 73 | 4b | 0 | 0 | Not Available | Nevi & Melanomas | Primary | scalp |
IPIMEL348.T1 | Female | White | Non Hispanic or Latino | 29 | 67 | X | 1b | 0 | G1: Well differentiated (low grade) | Not Available | Primary | Left groin extranodal |
IPIMEL353.T1 | Male | White | Non Hispanic or Latino | 36 | 69 | 4a | 2 | 1c | Not Available | Not Available | Primary | scalp |
IPIPNET005.T1 | Male | White | Non Hispanic or Latino | 32 | 33 | 2 | 1 | G1: Well differentiated (low grade) | NET | Primary | Pancreas | |
IPIPNET009.T1 | Female | Black or African American | Non Hispanic or Latino | 32 | 39 | 2 | 0 | G1: Well differentiated (low grade) | NET | Primary | Pancreas | |
IPIPNET010.T1 | Female | White | Non Hispanic or Latino | 22 | 65 | 3 | 0 | G1: Well differentiated (low grade) | NET | Primary | Pancreas |