Archetype Feature Distributions
| Tcells | Myeloid | Stromal | Treg | CD4 Tcells | CD8 Tcells | Monocytes | Macrophages | cDC2 | cDC1 |
|---|---|---|---|---|---|---|---|---|---|
| High | Low | Low | Varibale | Very High | Low | High | Low | Very High | Very High |
Potential Origin of this Archetype
Lymph node establishment, Tertiary Lymphoid Structures (TLSs), DCs, Conventional CD4 Tcells, B Cells Axis, Sustained by CCL28 signalling
Archetype Tumor transcriptomic program
Nervous system, Metastasis
Archetype Chemokines Expressed
CCL28, CCR10
Archetype Immune Transcriptomic Programs
High in B cells, High in DCs, High in Ag-Presentation/Co-Stim
Immune Archetype Gene Signature
Table of Archetype Feature Scores
Table of Archetype FEATURe flow Populations
Table of Archetype non feature flow Populations
Histology Abbreviations
ADC = Adenocarcinoma NOS HC = Hepatocellular Carcinoma, NOS
| Sample | Gender | Race | Ethnicity | BMI | Age | T Stage | N Stage | M Stage | Grade | Histology | Tumor type | Extraction Site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IPIHEP016.T1 | Male | White | Non Hispanic or Latino | 22 | 26 | 3b | 1 | X | Not Available | HC | Metastasis | liver |
| IPILUNG030.T2 | Female | Other | Non Hispanic or Latino | 39 | 61 | 1b | 0 | G3: Poorly differentiated (high grade) | ADC | Primary | ||
| IPIMEL069.T1 | Male | White | Non Hispanic or Latino | 20 | 48 | 1 | 3 | 0 | Not Available | Nevi & Melanomas | Metastasis | left groin |
| IPIMEL273.T1 | Male | White | Non Hispanic or Latino | 39 | 33 | 2 | 2a | 0 | Not Available | Not Available | Metastasis | Left axilla |
| IPIMEL288.T1 | Male | Other | Hispanic or Latino | 31 | 46 | 3 | 0 | 0 | Not Available | Not Available | Metastasis | right axillary |
| IPIMEL298.T1 | Female | Not Reported | Non Hispanic or Latino | 25 | 59 | X | X | 1b | Not Available | Not Available | Primary | Right groin soft tissue |