Archetype Feature Distributions
| Tcells | Myeloid | Stromal | Treg | CD4 Tcells | CD8 Tcells | Monocytes | Macrophages | cDC2 | cDC1 |
|---|---|---|---|---|---|---|---|---|---|
| High | High | Low | Medium | Low | Very high | Very high | Low | Variable | High |
Potential Origin of this Archetype
Acute inflamation in NK cells, Monocytes, cDC1, CD8 Tcells sustained by IFN/CCR2 signaling
Acute viral infection
Archetype Tumor transcriptomic program
IFN Signaling, SASP, EMT
Archetype Chemokines Expressed
XCL1, XCL2, XCR1, CXCL2, CXCR1
Archetype Immune Transcriptomic Programs
Very high in NK cells and tissue resident Tregs. Low exhaustion
Table of Archetype Feature Scores
Immune Archetype Gene Signature
Table of Archetype FEATURE Flow Populations
Table of Archetype Non feature Flow Populations
Histology Abbreviations
C = Carcinoma NOS LS = Mild Liver Steatosis CCC = Clear Cell Carcinoma NOS LMS = Leiomyosarcoma
| Sample | Gender | Race | Ethnicity | BMI | Age | T Stage | N Stage | M Stage | Grade | Histology | Tumor type | Extraction Site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IPIBLAD005.T1 | Male | White | Non Hispanic or Latino | 21 | 77 | 3b | 0 | G3: Poorly differentiated (high grade) | C | Primary | Bladder | |
| IPICRC054.T1 | Male | White | Non Hispanic or Latino | 25.76 | 45 | Not Available | Not Available | Not Available | Not Available | LS | ||
| IPIKID057.T1 | Female | Other | Non Hispanic or Latino | 42 | 63 | 2b | X | G2: Moderately differentiated (intermediate grade) | CCC | Primary | left kidney | |
| IPIKID069.T1 | Male | White | Non Hispanic or Latino | 31 | 48 | 3a | 0 | G3: Poorly differentiated (high grade) | CCC | Primary | right kidney | |
| IPIKID071.T1 | Male | White | Hispanic or Latino | 31 | 63 | 3b | 1 | G2: Moderately differentiated (intermediate grade) | CCC | Primary | right kidney | |
| IPIKID077.T1 | Female | White | Non Hispanic or Latino | 23 | 87 | 1a | X | G2: Moderately differentiated (intermediate grade) | CCC | Primary | left kidney | |
| IPIKID089.T1 | Female | White | Hispanic or Latino | 25 | 79 | 3a | 0 | G4: Undifferentiated (high grade) | CCC | Primary | kidney | |
| IPIKID095.T1 | Male | White | Non Hispanic or Latino | 24 | 48 | 1a | 0 | G2: Moderately differentiated (intermediate grade) | CCC | Primary | right kidney | |
| IPIKID103.T1 | Male | Asian | Non Hispanic or Latino | 21 | 65 | 3a | X | G3: Poorly differentiated (high grade) | CCC | Primary | left kidney | |
| IPIKID104.T1 | Male | Other | Hispanic or Latino | 29 | 70 | 3a | X | G2: Moderately differentiated (intermediate grade) | CCC | Primary | left kidney | |
| IPIKID109.T1 | Male | White | Non Hispanic or Latino | 25 | 84 | 3a | 0 | G3: Poorly differentiated (high grade) | CCC | Primary | right kidney | |
| IPISRC011.T1 | Male | White | Non Hispanic or Latino | 26 | 75 | Not Available | Not Available | Not Available | G1: Well differentiated (low grade) | LMS | Metastasis | liver |