Archetype Feature Distributions
Tcells | Myeloid | Stromal | Treg | CD4 Tcells | CD8 Tcells | Monocytes | Macrophages | cDC2 | cDC1 |
---|---|---|---|---|---|---|---|---|---|
Variable | HIgh | High | Very High | HIgh | Low | Low | Very High | Variable | Low |
Potential Origin of this Archetype
Tissue repair, Senescence, Tissue resident T cells, M2-like Macrophage, Sustained by IFN and TGFB signalling
Archetype Tumor transcriptomic program
IFN Signalling, SASP, Tissue repair
Archetype Chemokines Expressed
CCL2, CCR2, CCL17, CCL16, CCL19, CCL21, CCL22, CCR6, CCR7, CXCL9, CXCL11, CXCL12, CXCR3, CXCR4
Archetype Immune Transcriptomic Programs
M2-like phenotype, Tissue repair, Mast cells, IFN stimulated gene in myeloid cells
Immune Archetype Gene Signature
Table of Archetype Feature Scores
Table of Archetype FEATURE flow Populations
Table of Archetype non feature flow Populations
Histology Abbreviations
ADC = Adenocarcinoma NOS PSC = Papillary Serous Cystadenocarcinoma SCC = Squamous Cell Carcinoma NOS CCC = Clear Cell Carcinoma NOS EA = Endometriod Adenocarcinoma GST = Gastrointestinal stroma tumor
Sample | Gender | Race | Ethnicity | BMI | Age | T Stage | N Stage | M Stage | Grade | Histology | Tumor type | Extraction Site |
---|---|---|---|---|---|---|---|---|---|---|---|---|
IPICRC055.T1 | Female | White | Non Hispanic or Latino | 29.63 | 81 | 3 | 1 | G2: Moderately differentiated (intermediate grade) | ADC | Primary | sigmoid colon | |
IPIGYN045.T1 | Female | White | Non Hispanic or Latino | 31.53 | 79 | Not Available | Not Available | Not Available | G3: Poorly differentiated (high grade) | PSC | Primary | uterus |
IPIGYN069.T1 | Female | White | Non Hispanic or Latino | 23.78 | 69 | 3 | 1 | 0 | G1: Well differentiated (low grade) | GST | Primary | ovary |
IPIGYN082.T1 | Female | Black or African American | Non Hispanic or Latino | 34.39 | 64 | 3b | X | 1 | G3: Poorly differentiated (high grade) | PSC | Primary | uterus |
IPIGYN089.T1 | Female | Other | Hispanic or Latino | 52 | 50 | 1a | 0 | G1: Well differentiated (low grade) | EA | Primary | uterus | |
IPIHNSC050.T1 | Male | White | Non Hispanic or Latino | 14.31 | 69 | 4a | 2 | 0 | G2: Moderately differentiated (intermediate grade) | SCC | Primary | oral Cavity |
IPIHNSC057.T1 | Female | Black or African American | Non Hispanic or Latino | 26.04 | 63 | 2 | 2 | 0 | G2: Moderately differentiated (intermediate grade) | SCC | Primary | oral Cavity |
IPIHNSC075.T1 | Male | White | Non Hispanic or Latino | 25.3 | 75 | 2 | 0 | 0 | G3: Poorly differentiated (high grade) | ADC | Primary | major salivary gland |
IPIKID061.T1 | Male | White | Non Hispanic or Latino | 21 | 69 | 4 | 1 | G3: Poorly differentiated (high grade) | Other | Primary | right kidney | |
IPIKID098.T1 | Male | White | Hispanic or Latino | 22 | 59 | 3a | 1 | Not Available | CCC | Primary | right kidney | |
IPILUNG062.T1 | Female | White | Non Hispanic or Latino | 34 | 73 | 1b | X | G2: Moderately differentiated (intermediate grade) | ADC | Primary | upper lobe of right lung | |
IPILUNG074.T1 | Female | Asian | Non Hispanic or Latino | 23.8 | 57 | 2a | 2 | G3: Poorly differentiated (high grade) | ADC | Primary | upper lobe of left lung |